3-Pyrrolidinecarboxylic acid, 4-(2-methylphenyl)-, (3S,4R)- - Names and Identifiers
3-Pyrrolidinecarboxylic acid, 4-(2-methylphenyl)-, (3S,4R)- - Physico-chemical Properties
Molecular Formula | C12H15NO2
|
Molar Mass | 205.25 |
Storage Condition | 2-8°C(protect from light) |
3-Pyrrolidinecarboxylic acid, 4-(2-methylphenyl)-, (3S,4R)- - Introduction
(3S,4R)-4-o-tolylpyrrolidine-3-carboxylic acid is a chiral compound with the formula C11H11NO2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: The compound was a white crystalline solid.
-Melting point: about 110-112 ℃.
-Boiling point: about 352 ℃.
-Solubility: Soluble in organic solvents, such as ethanol, chloroform and dichloromethane, insoluble in water.
Use:
(3S,4R)-4-o-tolylpyrrolidine-3-carboxylic acid is an important intermediate compound, which is commonly used in the fields of medicine, pesticide and organic synthesis. It can also be used as chiral acid catalyst, catalyst support and chiral detector in organic synthesis.
Preparation Method:
(3S,4R)-4-o-tolylpyrrolidine-3-carboxylic acid has various preparation methods, but the most common method is to synthesize it by catalytic hydroxycarboxylation reaction. The synthesis method can use the enolone form of pyrrolidine to react with toluic acid, and obtain the target product through selective reduction, recrystallization and other steps.
Safety Information:
There are few experimental data and literatures about the safety information of (3S,4R)-4-o-tolylpyrrolidine-3-carboxylic acid. In general, as a chemical substance, it is necessary to observe safe practice and pay attention to personal protective measures, such as wearing protective glasses, gloves and protective clothing. At the same time, care should be taken to avoid contact with the skin, inhalation or into the eyes during use, storage and handling. If exposed or inhaled, flush immediately with plenty of water and seek medical help.
Please note that the above information is for reference only. Please refer to the safety data sheets and laboratory operating instructions of the relevant chemicals for specific operation.
Last Update:2024-04-09 21:54:55